Endocrine Abstracts

Background: Vitamin-D deficiency and type 2 diabetes (T2D) are common in South Asians (SA). The diagnosis of a vitamin-D deficiency in the setting of a chronic disease depends on a high index of suspicion and adequate investigation. This involves bone profile, occasionally in conjunction with serum 25-hydroxyvitamin-D. The ability of routine investigations to identify vitamin-D deficient patients have not been widely studied.Aims: To assess the ability o...

The association of low body weight due to excessive exercise and/or eating disorders, and hypothalamic amenorrhoea is well documented. Delayed or arrest of puberty may occur if low body weight occurs before or during puberty. Normal menstruation is restored once a healthy body weight is regained. In this case, body weight normalised but ovarian function did not.A 34-year-old woman attended our thyroid clinic for subclinical hypothyroidism following an ep...

Type 1B pseudohypoparathyroidism is characterised by renal resistance to parathyroid hormone in the absence of other endocrine or physical abnormalities. We present a 36-year-old lady with pseudohypoparathyroidism diagnosed aged seven following seizures with hypocalcaemia, hyperphosphataemia, elevated alkaline phosphatase, elevated parathyroid hormone (PTH) at 700 pg/mL (<120) and no cyclic AMP response to bovine PTH. There was no family history or diagnostic phenotypic fe...